“Dopaminergic Neurotransmission and Cognitive Bias in Pathological Gambling”

Principal Investigator: Jakob Linnet, Ph.D., Aarhus University Hospital, Denmark
Awarded $149,185 in 2006

Aim: Test the hypothesis that pathological gamblers have a lower dopamine concentration and a higher dopamine release during gambling compared with healthy controls; that other factors, such as personality traits such as sensation seeking, influence the dopamine release during gambling; and, that dopamine binding potential and occupancy are associated (directly or indirectly) with cognitive bias of gambling performance.

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Linnet, J., Peterson, E., Daudet, D.J., Gjedde, A., & Moller, A. (2010). Dopamine release in ventral striatum of pathological gamblers losing money. Acta Psychiatrica Scandinavica, 122, 326-333.

Linnet, J., Møller, A., Peterson, E., Gjedde, A., & Doudet, D. (2011). Dopamine release in ventral striatum during Iowa Gambling Task performance is associated with increased excitement levels in pathological gambling. Addiction, 106(2), 383-390.

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Year: 2006
Type: Project Grants